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Product Status Compound Cissus Quadrangularis, Pet Sang Khat, Asthisandhana
Type Food supplement
Main Ingredients Compound Cissus Quadrangularis
Weight 80 grams
Price $9.35
Shipping FREE worldwide shipping
Size 100 capsules
Ideal For Obesity, Hemorrhoids, Flatulence, Lower blood sugar, Lower cholesterol


Recent studies show that an extract of Cissus quadrangularis (syn. Vitis quadrangularis) aerial stems can help produce weight loss, lower blood glucose, and reduce total and LDL (bad) cholesterol in obese patients.1,2 Cissus quadrangularis is an indigenous medicinal plant of India in the grape family (Vitaceae) that has traditionally been used as an Asian culinary vegetable for curries and chutneys and as an herbal remedy in traditional Ayurvedic medicinal practice (where it is known as asthisandhana). Its standardized common name, according to the American Herbal Products Association, is winged treebine; other common names are bonesetter and Veldt grape.3
The results of one study were presented at the First World Congress on Therapies against Obesity, held May 18-19, in Paris.1 In that double-blind, placebo-controlled trial, 68 obese participants received either 300 mg daily of a propriety extract of Cissus quadrangularis called Cissus CQR-300 (Soy Labs LLC, Fairfield, CA) or a placebo for 6 weeks. They were encouraged to maintain their normal diets and physical activities and to keep daily food and activity diaries. Participants in the Cissus CQR-300 group experienced an average weight loss of 10.6 pounds, compared to an average gain of 2.6 pounds among those taking the placebo.4 Those given Cissus CQR-300 also reduced their body mass index (BMI, 4.1%), fasting blood glucose levels (14.6%), total cholesterol (18%), LDL cholesterol (29%), triglycerides (21.6%), and fat metabolites (45.5%), in addition to increasing their HDL (good) cholesterol (21.1%), 5-hydroxytryptamine/serotonin (5-HT, 53.3%), and serum creatinine (23.5%). The placebo group experienced a small decrease in triglycerides (3.3%) and a moderate increase in 5-HT (17%). (Since this trial has not yet been published and subjected to formal peer review, it is possible that the values reported here may undergo revision, i.e., if this study is submitted for publication.)
The results of the second study were published in the September issue of Lipids in Health and Disease.2 This randomized, double-blind, placebo-controlled trial involved 123 overweight and obese participants, and was conducted over 8 weeks. The trial’s 92 obese participants were divided into 3 groups: one group was given placebo, another received 2 daily doses (514 mg each) of a Cissus formulation (containing Cissus quadrangularis, green tea [Camellia sinensis], soy, chromium, selenium, and B-vitamins, supplied by Gateway Health Alliances, Fairfield, CA), and the third group took the same Cissus formulation with a calorie-controlled diet. The 31 overweight participants formed a fourth group, and they took the Cissus formulation without a controlled diet. The participants in the placebo group lost, on average, about 5 pounds over the 8 week trial, whereas the overweight group lost 8.2 pounds, the obese group taking only the Cissus formulation lost 14.6 pounds, and the obese group on the formulation with diet lost 17.9 pounds. All 3 treatment groups experienced a decrease in triglycerides, C-reactive protein, and fasting blood glucose levels. Total cholesterol declined 5 mg/dl for the placebo group, 28.7 mg/dl for the overweight group, 43 mg/dl for the obese group on formulation/no diet, and 44.5 mg/dl for the obese group on formulation/diet. The authors conclude that, “Our results support the hypothesis that the use of a Cissus quadrangularis formulation has efficacy in the management of weight loss and metabolic syndrome, particularly for central obesity.”


1. Oben J, Mandob D, Fomekong G, Agbor G, Momo C. The effect of an extract of Cissus quadrangularis (Cylaris) on weight and serum lipids in obese patients in Cameroon: a randomized double blind clinical trial [abstract]. Paper presented at: First World Congress on Therapies against Obesity; May 18-19, 2006; Paris.
2. Oben J, Kuate D, Agbor G, Momo C, Talla X. The use of a Cissus Quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids in Health and Disease. 2006;5:24.
3. McGuffin M, Kartesz JT, Leung AY, Tucker AO. American Herbal Products Association’s Herbs of Commerce, 2nd ed. Silver Spring, MD: American Herbal Products Association, 2000.
4. New study demonstrates weight loss and health benefits of CardioTrim [press release]. Fairfield, CA: Soy Labs LLC; August 30, 2006.

2 capsules to be taken each time, after breakfast, lunch and dinner. Bottle contains enough for 16 days. All natural product. No added chemicals.

At Beautique Thai, we believe strongly in the efficacy of natural remedies to maintain the body's balance. Herbal remedies are steeped in history, and sometimes in myth. And many products are sold on the premise that they may help certain conditions. We try to restrict our recommendations to those that have good, recently researched, basis in fact. In addition to the use of any product, you should maintain a healthy lifestyle by eating fresh fruit and vegetables every day, drinking plenty of water, and undertaking good aerobic exercise for a minimum of 30 minutes per day. If you are taking any medication, we strongly suggest you consult your medical practitioner before adding any new oral remedy, herbal or otherwise.

If you have any questions about this or any other Beautique Thai product, mail us at We will do our best to help you.



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