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Item #: thp100296
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Product Status Thunbergia Laurifolia, Ya Rang Jued
Type Herbal Tea
Main Ingredients Thunbergia Laurifolia
Weight 80 grams
Shipping FREE  shipping worldwide
Size 40 teabags
Ideal For Antipyretic (fever), Diabetes, Alcohol/Drug addiction, Liver recovery

Several kinds of medicinal plants have been used to treat diabetes mellitus. In a recent study, Thunbergia laurifolia Linn. (purple flower strain) were tested for hypoglycemic activity in rats. The effects on the reproductive system and the histology of the pancreas were also investigated. The hypoglycemic properties of the aqueous extract from the leaves (60 mg/ml/day) were evaluated in normoglycemic and alloxan-induced diabetic rats. The results showed that high blood glucose levels of diabetic rats were associated with severe destruction of beta-cells (insulin-secreting cells) in the islet of Langerhans. The 15-day-treatment of T. laurifolia extract decreased levels of blood glucose in diabetic rats. The recovery of some beta-cells was found in diabetic rats treated with the extract, although not completely normal. Whether T. laurifolia leaf contains insulin-like substance(s) which directly act as hypoglycemic agents, or contains substances that induce the regenerative process of beta-cells remains to be further investigated. Alteration of the reproductive system was also observed in diabetic rats, but it was not improved by treatment with T. laurifolia extract.

Publication Type: Journal Article

Journal: The Southeast Asian journal of tropical medicine and public health (Southeast Asian J Trop Med Public Health), published in Thailand. (Language: eng)

Reference: 2004-; vol 35 Suppl 2 (issue ) : pp 53-8

Dates: Created 2005/05/23; Completed 2005/06/24

Recent study for efficacy in alcohol and drug rehabilitation.

Watchareewan Thongsaard (1), Charles A. Marsden2, Peter Morris3, Malcolm Prior3 and Yasmene B. Shah2

(1)  Department of Physiology, Faculty of Medicine, Srinakharinwirot University, Sukhumvit 23, Wattana, Bangkok, 10110, Thailand
(2)  School of Biomedical Science, The University of Nottingham, Nottingham, NG7 2UH, UK
(3)  Magnetic Resonance Centre, School of Physics and Astronomy, The University of Nottingham, Nottingham, NG7 2RD, UK

Received: 26 November 2004  Accepted: 25 April 2005  Published online: 2 July 2005


Rationale   Thunbergia laurifolia Linn. (TL) is an herbal medicine used to treat alcohol and drug addiction in Thai traditional medicine. A previous study demonstrated that an extract of TL increases rat striatal dopamine release in vitro.
Objectives  This study determined whether a methanol extract of TL altered rat brain region activity using in vivo functional nuclear magnetic resonance imaging (fMRI) in a manner consistent with the observed effects in vitro on dopamine release.
Methods  fMRI was performed on a 2.35-T Bruker MR system. MR images were acquired from rat brain using the rapid acquisition relaxation enhanced sequence (field of view 50 mm). The imaging parameters used for the anatomical scan yielded an in-plane spatial resolution of 0.2×0.2 mm. Consecutive single-slice functional imaging over the rat brain investigated the changes in signal intensity in various parts of the brains induced by TL (200 mg/kg, i.p.) or vehicle administration.
Results  These demonstrate that TL increased signal intensity in various brain areas such as nucleus accumbens, globus pallidus, amygdala, frontal cortex, caudate putamen and hippocampus. These are similar to those reported previously to show effects after either cocaine or amphetamine administration. Physiological variables were not affected by the injection of TL (200 mg/kg, i.p.), but there was a small decrease in arterial blood pressure.
Conclusions  The results indicate that TL increases significant neuronal activity in specific brain regions responsible for reward and locomotor behaviour (fixed-effect analysis); however, there is no significant difference between TL and vehicle-treated groups with random-effect analysis (population statistic). The active compound(s) in TL responsible for the pharmacological effects of TL remain to be identified.
Recent study in liver recovery
Pramyothin P, Chirdchupunsare H, Rungsipipat A, Chaichantipyuth C.

Pharmacological Action of Natural Products Research Unit, Department of Pharmacology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.

Primary cultures of rat hepatocyte and rats were used as the in vitro and in vivo models to evaluate the hepatoprotective activity of aqueous extract from Thunbergia laurifolia (TLE). Ethanol was selected as hepatotoxin. Silymarin (SL) was the reference hepatoprotective agent. In the in vitro study, MTT reduction assay and release of transaminases (ALT and AST) were the criteria for cell viability. Primary cultures of rat hepatocyte (24 h culturing) were treated with ethanol (96 microl/ml) and various concentrations of TLE (2.5, 5.0, 7.5 and 10.0 mg/ml) or SL (1, 2 and 3 mg/ml) for 2 h. Ethanol decreased MTT (%) nearly by half. Both TLE and SL increased MTT reduction and brought MTT (%) back to normal. Ethanol induced release of ALT and AST was also reduced by TLE (2.5 and 5.0 mg/ml) and SL (1 mg/ml). In the in vivo study, serum transaminases, serum triglyceride (STg) together with hepatic triglyceride (HTg) and histopathological examination were the criteria for evidences of liver injury. Ethanol (4 g/(kg day), po for 14 days) caused the increase in ALT, AST, HTg and centrilobular hydropic degeneration of hepatocytes. TLE at 25 mg/(kg day), po, or SL at 5 mg/(kg day), po, for 7 days after ethanol enhanced liver cell recovery by bringing HTg, ALT and/or AST back to normal. These results suggest that TLE and SL possess the hepatoprotective activity against ethanol induced liver injury in both primary cultures of rat hepatocyte and rats.

At Beautique Thai, we believe strongly in the efficacy of natural remedies to maintain the body's balance. Herbal remedies are steeped in history, and sometimes in myth. And many products are sold on the premise that they may help certain conditions. We try to restrict our recommendations to those that have good, recently researched, basis in fact. In addition to the use of any product, you should maintain a healthy lifestyle by eating fresh fruit and vegetables every day, drinking plenty of water, and undertaking good aerobic exercise for a minimum of 30 minutes per day. If you are taking any medication, we strongly suggest you consult your medical practitioner before adding any new oral remedy, herbal or otherwise.

If you have any questions about this or any other Beautique Thai product, mail us at We will do our best to help you.



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